Month: September 2015
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Single-cell analyses of transcriptional heterogeneity during drug tolerance transition in cancer cells by RNA sequencing
Abstract: The acute cellular response to stress generates a subpopulation of reversibly stress-tolerant cells under conditions that are lethal to the majority of the population. Stress tolerance is attributed to heterogeneity of gene expression within the population to ensure survival of a minority. We performed whole transcriptome sequencing analyses of metastatic human breast cancer cells…
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No reason to retire
By Peggy Townsend, UCSC Public Information Office On a January day in 1969, Gary Griggs, then 25, donned a coat and tie and entered a lecture hall on the nascent UC Santa Cruz campus. What he found inside were 260 scruffy but idealistic students — most of them long-haired, many with dogs. Griggs, who had…
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UC Santa Cruz Genomics Institute partners with Microsoft to accelerate biomedical research
By Tim Stephens, UCSC Public Information Office The UC Santa Cruz Genomics Institute has formed a partnership with Microsoft that will help researchers accelerate analysis of genomic information using the company’s cloud computing platform, Microsoft Azure. The collaboration provides the Genomics Institute with access to new compute, data storage, and analysis capabilities, enabling researchers to…
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Biologist Susan Strome to give annual Faculty Research Lecture
Monday, September 14, 2015 By Tim Stephens, UCSC Public Information Office Susan Strome, distinguished professor of molecular, cell and developmental biology at UC Santa Cruz, will deliver the 50th annual UCSC Faculty Research Lecture on Friday, September 25, at 7 p.m. in the Music Recital Hall. Entitled “Beyond the DNA Code: Transmission of developmental instructions…
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Evolutionary arms race discovered in human DNA
By Jacob Comeaux, UC Santa Cruz science writing student There’s a war raging within each of the 37.2 trillion cells in your body. Microscopic war is not a novel notion—our immune system fights off pernicious pathogens all the time. But scientists based at the UC Santa Cruz Genomics Institute have shown that our DNA, the…
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Dogs, cats, and big-wave surfers: Healthy heart lessons from animals and athletes
By Tim Stephens, UC Santa Cruz Public Information Office For over 30 years, Terrie Williams has been studying exercise physiology in wild animals: African lions and wild dogs, dolphins and whales, coyotes and mountain lions, as well as a few human athletes. She has put mountain lions on treadmills and strapped heart-rate monitors onto big-wave…