Month: June 2020
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AMELIE speeds Mendelian diagnosis by matching patient phenotype and genotype to primary literature
[et_pb_section fb_built=”1″ _builder_version=”4.2.2″ custom_padding=”0px|||||”][et_pb_row _builder_version=”4.2.2″][et_pb_column type=”4_4″ _builder_version=”4.2.2″][et_pb_text _builder_version=”4.2.2″ hover_enabled=”0″] Finding a gene in the stacks Genetic disease diagnosis can be time-consuming because of the extensive literature searching required. To speed this process, Birgmeier et al. developed AMELIE (Automatic Mendelian Literature Evaluation), an end-to-end machine learning approach with web interface that finds relevant literature supporting the disease…
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Comprehensive Analysis of Genetic Ancestry and Its Molecular Correlates in Cancer
[et_pb_section fb_built=”1″ _builder_version=”3.25.3″][et_pb_row _builder_version=”3.25.3″][et_pb_column type=”4_4″ _builder_version=”3.25.3″][et_pb_text _builder_version=”4.2.2″ hover_enabled=”0″] Highlights This large analysis identified ancestry correlates in cancer Ancestry-associated artifacts and confounders were identified Ancestry effects are profoundly tissue specific Rates of FBXW7, VHL, and PBRM1 mutations and immune activity vary by ancestry Summary We evaluated ancestry effects on mutation rates, DNA methylation, and mRNA and…
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Solved: For 43 years, she was ‘Precious’ Jane Doe
She was murdered near Everett in 1977. Years of detective work finally revealed her name: Lisa Roberts, 17.
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NHGRI commemorates 20th anniversary of White House event announcing draft human genome sequence
[et_pb_section fb_built=”1″ _builder_version=”3.25.3″ custom_padding=”0px|||||”][et_pb_row _builder_version=”3.25.3″ min_height=”1793px”][et_pb_column type=”4_4″ _builder_version=”3.25.3″][et_pb_text _builder_version=”4.2.2″ min_height=”1779px”] Prabarna Ganguly, Ph.D. | NHGRI News | June 26, 2020 The signature goal of the Human Genome Project (HGP) was to generate a sequence of the three billion letters (A, C, G and T) in the human DNA instruction book. The multidisciplinary, international consortium worked…
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Angela Brooks Named Director, Diversity, for the Genomics Institute
[et_pb_section fb_built=”1″ _builder_version=”4.2.2″ custom_padding=”0px|||||”][et_pb_row _builder_version=”4.2.2″][et_pb_column type=”4_4″ _builder_version=”4.2.2″][et_pb_text _builder_version=”4.2.2″] Dr. Brooks has enhanced diversity and inclusion in STEM by creating new training opportunities for students from underrepresented groups UC Santa Cruz Genomics Institute | June 22, 2020 As a splicing specialist, Angela Brooks’s goal is to identify weaknesses in the cancer genome. As a research community…
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Domain-Specific Hardware Accelerators Communications of the ACM
[et_pb_section fb_built=”1″ _builder_version=”4.2.2″ custom_padding=”6px|||||”][et_pb_row _builder_version=”4.2.2″][et_pb_column type=”4_4″ _builder_version=”4.2.2″][et_pb_text _builder_version=”4.2.2″ hover_enabled=”0″] From the simple embedded processor in your washing machine to powerful processors in data center servers, most computing today takes place on general-purpose programmable processors or CPUs. CPUs are attractive because they are easy to program and because large code bases exist for them. The…
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The Human Genome Project in 2020 Hindsight
[et_pb_section fb_built=”1″ _builder_version=”3.25.3″ min_height=”1122px” custom_padding=”0px|||||”][et_pb_row _builder_version=”4.2.2″][et_pb_column _builder_version=”4.2.2″ type=”4_4″][et_pb_text _builder_version=”4.2.2″ hover_enabled=”0″] Mark Wilson / Newsmakers/Getty Images Two decades after the working draft of the human genome was completed, it is clearer than ever that analysis of the text is just getting started Julianna LeMieux, PhD | GEN | June 5, 2020 On June 26, 2000, President…
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Statement on Racial Justice
[et_pb_section fb_built=”1″ _builder_version=”4.2.2″ custom_padding=”0px|||||” hover_enabled=”0″][et_pb_row _builder_version=”4.2.2″][et_pb_column type=”4_4″ _builder_version=”4.2.2″][et_pb_text _builder_version=”4.2.2″] June 10, 2020 | UC Santa Cruz Genomics Institute We are writing to express our outrage and sorrow at the recent murders of George Floyd, Breonna Taylor, and Ahmaud Arbery, and to condemn the systemic racism that is at the root of ongoing violence against Black…
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Campus, Santa Cruz Community Health unite to test underserved community members
[et_pb_section fb_built=”1″ _builder_version=”4.2.2″ custom_padding=”0px|||||”][et_pb_row _builder_version=”4.2.2″][et_pb_column _builder_version=”4.2.2″ type=”4_4″][et_pb_text _builder_version=”4.2.2″ hover_enabled=”0″] June 04, 2020 | UCSC | Scott Hernandez-Jason Compelled by values of social justice and equity, UC Santa Cruz and Santa Cruz Community Health, a nonprofit primary care provider for low-income patients, are working together to test the area’s underserved residents for COVID-19. As news outlets published…
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UC COVID-19 seed funding supports UCSC coronavirus genome browser
[et_pb_section fb_built=”1″ _builder_version=”3.25.3″ custom_padding=”14px|||||”][et_pb_row _builder_version=”3.25.3″][et_pb_column type=”4_4″ _builder_version=”3.25.3″][et_pb_text _builder_version=”4.2.2″ hover_enabled=”0″] June 05, 2020 | Tim Stephens | UCSC The UC Santa Cruz Genomics Institute’s Genome Browser Team has received seed funding from the UC Office of the President for its work on the UCSC Genome Browser for SARS-CoV-2, which supports biomedical research aimed at developing therapeutics…
