Month: November 2020
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UC Santa Cruz teams up, pools data to fight stomach cancer
The new genetic variant exchange aims to advance science and patient survival by combining vast amounts of gene variant data with corresponding clinical data. UCSC | November 24, 2020 Coinciding with Stomach Cancer Awareness Month in November, the UC Santa Cruz Genomics Institute is teaming up with the patient advocacy nonprofit No Stomach For Cancer…
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List of most highly cited researchers features 19 UCSC scientists and engineers
Tim Stephens | UCSC | November 18, 2020 A new list of the world’s most highly cited researchers includes 19 scientists and engineers at UC Santa Cruz. The 2020 Highly Cited Researchers list, released November 18 by Clarivate’s Web of Science Group, identifies global research scientists and social scientists who have demonstrated exceptional influence as reflected through their…
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A comparative genomics multitool for scientific discovery and conservation
Zoonomia Consortium Abstract The Zoonomia Project is investigating the genomics of shared and specialized traits in eutherian mammals. Here we provide genome assemblies for 131 species, of which all but 9 are previously uncharacterized, and describe a whole-genome alignment of 240 species of considerable phylogenetic diversity, comprising representatives from more than 80% of mammalian families.…
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Dense sampling of bird diversity increases power of comparative genomics
Shaohong Feng, Josefin Stiller, […] Guojie Zhang Abstract Whole-genome sequencing projects are increasingly populating the tree of life and characterizing biodiversity. Sparse taxon sampling has previously been proposed to confound phylogenetic inference, and captures only a fraction of the genomic diversity. Here we report a substantial step towards the dense representation of avian phylogenetic and…
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Progressive Cactus is a multiple-genome aligner for the thousand-genome era
Joel Armstrong, Glenn Hickey, Mark Diekhans, Ian T. Fiddes, Adam M. Novak, Alden Deran, Qi Fang, Duo Xie, Shaohong Feng, Josefin Stiller, Diane Genereux, Jeremy Johnson, Voichita Dana Marinescu, Jessica Alföldi, Robert S. Harris, Kerstin Lindblad-Toh, David Haussler, Elinor Karlsson, Erich D. Jarvis, Guojie Zhang, and Benedict Paten Abstract New genome assemblies have been arriving…
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Coronavirus: A month-by-month look at California’s path forward
In the first installment of a new series “Coronavirus: The Path Forward,” we offer a month-by-month forecast of some key moments in our likely future.By LISA M. KRIEGER | lkrieger@bayareanewsgroup.com | Bay Area News GroupA promising vaccine, with more to come. Improved tests. Better therapies. A new president with a more vigorous federal strategy and…
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New genome alignment tool empowers large-scale studies of vertebrate evolution
Important new studies of the evolution of birds and mammals relied on Progressive Cactus, a genome alignment tool developed at the UC Santa Cruz Genomics Institute By Tim Stephens |November 11, 2020 Three papers published November 11 in Nature present major advances in understanding the evolution of birds and mammals, made possible by new methods…