Month: May 2021
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Progress, Challenges, and Surprises in Annotating the Human Genome
CAPTION: Organizations that support the GRC assembly and its gene annotations. Abbreviations: e!, Ensembl Project; GRC, Genome Reference Consortium; HGNC, Human Genome Organisation (HUGO) Gene Nomenclature Committee; INSDC, International Nucleotide Sequence Database Collaboration; NCBI, National Center for Biotechnology Information; UCSC, University of California, Santa Cruz. Daniel R. Zerbino, Adam Frankish, and Paul Flicek | Annual…
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The Human Genome Project: 20 Years Later
The Agenda with Steve PaikinEpisode:The Human Genome Project at 20Aired: Mar 01, 2021 In February 2001, after a remarkable global effort, the Human Genome Project published its first draft in an effort to map the 3 billion big pairs of our entire genome. That was heralded as a massive accomplishment that would yield incredible dividends.…
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Ambitious Project Races to Read Genomes of 71,000 Species
Caption: Scientists can use genome sequencing to learn how to better protect critically endangered species such as the California condor. UCSC Genomics Institute researchers contribute to learning more about vertebrates Isabella Backman | MAY 12, 2021 | Good Times About 4 billion years ago, the first cellular life came into existence. Ever since, parents have…
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Ancient horse DNA reveals gene flow between Eurasian and North American horses
New findings show connections between the ancient horse populations in North America, where horses evolved, and Eurasia, where they were domesticated May 18, 2021 | Tim Stephens | UCSC A new study of ancient DNA from horse fossils found in North America and Eurasia shows that horse populations on the two continents remained connected through…
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The Human Genome Project: the Beginning of the Beginning
Michael S. Waterman | March 31, 2021 | Quantitative Biology In May 1985 there was at University of California Santa Cruz an influential meeting that was the first serious discussion of sequencing the entire human genome. The author was one of the participants and described the meeting and related issues. The Human Genome Project (HGP)…
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Vaccines track released for the UCSC SARS-CoV-2 Genome Browser
May 11, 2021 UC Santa Cruz Genomics Institute The UCSC Genome Browser team announced the release today of the Vaccines track for the UCSC SARS-CoV-2 Genome Browser. This track shows the alignment of three different mRNA vaccine sequences to the SARS-CoV-2 genome: The BioNTech/Pfizer BNT-162b2 sequence as published by the World Health Organization (WHO) The…
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New tools enable rapid analysis of coronavirus sequences and tracking of variants
UShER allows researchers to quickly see how a new viral sequence is related to all other variants of SARS-CoV-2, crucial information for tracking transmission dynamics Tim Stephens | May 10, 2021 | UCSC The COVID-19 pandemic has spurred genomic surveillance of viruses on an unprecedented scale, as scientists around the world use genome sequencing to…
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Oldest DNA sequences reveal how mammoths evolved
Caption: This illustration represents a reconstruction of the steppe mammoths that preceded the woolly mammoth, based on genetic analysis of ancient mammoth DNA. (Illustration by Beth Zaiken/Centre for Palaeogenetics) Analysis of ancient DNA sequences recovered from mammoth teeth reveal North American mammoths were descended from two earlier mammoth lineages February 17, 2021 | Tim Stephens…
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Alumni Weekend was a virtual smorgasbord for nostalgic Banana Slugs
Dan White | UCSC | April 28, 2021 Banana Slugs showed off their creativity and adaptability during last week’s all-virtual Alumni Week, a celebration that made the most of its online format and featured more than 70 live events from April 19–25. Sure, it’s nice to hug former roommates, sit down for a picnic lunch…