Author: Rose Miyatsu
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The Computational Genomics Platform (CGP) Provides Global Access to Genomic Data and Tools
In 2017, Benedict Paten and collaborators proposed the “Data Biosphere” as a means to substantially accelerate genomics and biomedical research by building cloud platforms where components are modular, open and based on community standards (such as those developed by the Global Alliance for Genomics and Health (GA4GH)). Each platform contains portals for secure access to…
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‘First line of defense’: UCSC’s COVID-19 testing lab ready to relocate, ramp up
Nick Ibarra | Lookout Santa Cruz | December 17, 2020 Already a pillar of testing capacity for both the campus and wider community, UCSC’s COVID-19 testing lab is prepping to grow as it moves into a new home. The UCSC Molecular Diagnostic Lab is expected to move off the main campus to a Westside Santa…
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Study Reveals Networks of Genes Involved in Congenital Heart Disease
The findings could point toward new ways to prevent or treat one of the most common birth defects Gladstone Institutes | December 14, 2020 SAN FRANCISCO, Dec. 14, 2020 /PRNewswire/ — Over two million babies, children, and adults in the United States are living with congenital heart disease—a range of birth defects affecting the heart’s structure…
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Nature’s 10: ten people who helped shape science in 2020
A COVID vaccine developer, an Arctic voyager and a prime minister are some of the people behind the year’s big research stories. 14 DECEMBER 2020 The Nature’s 10 list explores key developments in science this year and some of the people who played important parts in these milestones. Along with their colleagues, these individuals helped…
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Slugs lauded as Hometown Heroes
Slugs lauded as Hometown Heroes Chancellor, faculty, staff and alumni honored at Santa Cruz Works event Marc DesJardins | UCSC | December 02, 2020 UC Santa Cruz is well represented at this year’s Santa Cruz Works Hometown Heroes awards ceremony, with Chancellor Cynthia Larive, a host of faculty and staff members, and numerous alumni slated…
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UC Santa Cruz teams up, pools data to fight stomach cancer
The new genetic variant exchange aims to advance science and patient survival by combining vast amounts of gene variant data with corresponding clinical data. UCSC | November 24, 2020 Coinciding with Stomach Cancer Awareness Month in November, the UC Santa Cruz Genomics Institute is teaming up with the patient advocacy nonprofit No Stomach For Cancer…
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List of most highly cited researchers features 19 UCSC scientists and engineers
Tim Stephens | UCSC | November 18, 2020 A new list of the world’s most highly cited researchers includes 19 scientists and engineers at UC Santa Cruz. The 2020 Highly Cited Researchers list, released November 18 by Clarivate’s Web of Science Group, identifies global research scientists and social scientists who have demonstrated exceptional influence as reflected through their…
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A comparative genomics multitool for scientific discovery and conservation
Zoonomia Consortium Abstract The Zoonomia Project is investigating the genomics of shared and specialized traits in eutherian mammals. Here we provide genome assemblies for 131 species, of which all but 9 are previously uncharacterized, and describe a whole-genome alignment of 240 species of considerable phylogenetic diversity, comprising representatives from more than 80% of mammalian families.…
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Dense sampling of bird diversity increases power of comparative genomics
Shaohong Feng, Josefin Stiller, […] Guojie Zhang Abstract Whole-genome sequencing projects are increasingly populating the tree of life and characterizing biodiversity. Sparse taxon sampling has previously been proposed to confound phylogenetic inference, and captures only a fraction of the genomic diversity. Here we report a substantial step towards the dense representation of avian phylogenetic and…
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Progressive Cactus is a multiple-genome aligner for the thousand-genome era
Joel Armstrong, Glenn Hickey, Mark Diekhans, Ian T. Fiddes, Adam M. Novak, Alden Deran, Qi Fang, Duo Xie, Shaohong Feng, Josefin Stiller, Diane Genereux, Jeremy Johnson, Voichita Dana Marinescu, Jessica Alföldi, Robert S. Harris, Kerstin Lindblad-Toh, David Haussler, Elinor Karlsson, Erich D. Jarvis, Guojie Zhang, and Benedict Paten Abstract New genome assemblies have been arriving…
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Coronavirus: A month-by-month look at California’s path forward
In the first installment of a new series “Coronavirus: The Path Forward,” we offer a month-by-month forecast of some key moments in our likely future.By LISA M. KRIEGER | lkrieger@bayareanewsgroup.com | Bay Area News GroupA promising vaccine, with more to come. Improved tests. Better therapies. A new president with a more vigorous federal strategy and…
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New genome alignment tool empowers large-scale studies of vertebrate evolution
Important new studies of the evolution of birds and mammals relied on Progressive Cactus, a genome alignment tool developed at the UC Santa Cruz Genomics Institute By Tim Stephens |November 11, 2020 Three papers published November 11 in Nature present major advances in understanding the evolution of birds and mammals, made possible by new methods…