Author: Rose Miyatsu
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RNA Rescue challenge invites players to solve puzzles and advance RNA therapeutics
Researchers at UC Santa Cruz have developed a new puzzle challenge for the online game Eterna, enlisting players to help design a novel RNA drug to treat hemophilia A Tim Stephens | UCSC | February 21, 2023 Researchers at UC Santa Cruz working to develop novel RNA-based medicines are teaming up with a new group…
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Researcher wins inaugural NHGRI award for DEIA Innovation in the Genomics Workforce
Emily Cerf | UCSC | February 21, 2023Ann McCartney, a research scientist at the UC Santa Cruz Genomics Institute, has always wanted to be part of building a better world. As career led her to becoming a genomicist, she has focused this passion into a commitment to equity in scientific research, particularly in advancing genomic…
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Beth Shaprio Plans to Revive Dodo Bird
By pursuing the problem of dodo de-extinction, Beth Shapiro and Colossal Biosciences hope to develop critically needed tools for avian genomics, including for the genetic rescue of currently threatened species. In this way, a 21st-century dodo may assist all avian conservation.
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The human genome needs updating. But how do we make it fair?
Healthcare’s standard genome is mostly based on one American. As we enter the era of personalised medicine, this bias has drawbacks for much of the world’s population Betsy Reed | The Guardian | January 29, 2023 In June 2000, Bill Clinton, the then US president, stood smilingly next to the leaders of the Human Genome…
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Researchers Go Beyond Gene Variant Analysis With Nascent Pangenome-Based Methods
Andrew P. Han | genomeweb | January 30, 2023 NEW YORK – Graph-based genomes, such as the one being built by the Human Pangenome Reference Consortium (HPRC), are already being used to do more than just genetic variant analysis. Read on genomeweb.
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UCSC Genome Browser selected to first-ever Global Core Biodata Resource List
The Global Core Biodata Resources list represents a collection of 37 open-source resources whose long-term funding and sustainability is critical to life science and biomedical research worldwide. The Browser was chosen as a vital tool for researchers in the biosciences.
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Long-standing genomic mystery about the origins of introns explained in new study
UCSC scientists point to introners as the source of the vast majority of introns, a source of molecular complexity unique to eukaryotes Emily Cerf | UCSC | November 29, 2022 One of the most long-standing, fundamental mysteries of biology surrounds the poorly understood origins of introns. Introns are segments of noncoding DNA that must be…
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Modular automated microfluidic cell culture platform reduces glycolytic stress in cerebral cortex organoids
Time line chart of the human cerebral organoid generation protocol over the span of 18 days Abstract Organ-on-a-chip systems combine microfluidics, cell biology, and tissue engineering to culture 3D organ-specific in vitro models that recapitulate the biology and physiology of their in vivo counterparts. Here, we have developed a multiplex platform that automates the culture…
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Braingeneers develop novel method to automate the growth of brain tissue organoids on a chip
The new system can increase reproducibility in cerebral organoid research and shows promise for lowering levels of cellular stress Emily Cerf | UCSC | November 28, 2022 A team of engineers at UC Santa Cruz has developed a new method for remote automation of the growth of cerebral organoids – miniature, three-dimensional models of brain…
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Remote-controlled microscopes bring complex biology education to students worldwide
UC Santa Cruz researchers have developed a method for using remote-controlled, internet-connected microscopes to enable students anywhere in the world to participate in designing and carrying out biology experiments, increasing access to project-based learning in STEM.
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Closing cell—and academic—gaps
UCSC’s Genomics Institute opens up the world of bioinformatics and programming to students Bayan Parrenas Shimizu | UCSC | November 04, 2022 Launched just last year, UC Santa Cruz Genomics Institutes summer research programs are already seeing unparalleled success. Roman Reggiardo, Biomolecular Engineering and Mathematics Program Ph.D. candidate and Bioinformatics Summer Bridge instructor, witnessed this…
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Postdoctoberfest Spotlight: Jean Monlong
It is Postdoctoberfest! This week, we are celebrating the vital contributions that postdoctoral scholars make to UC Santa Cruz, and to the advancement of science more broadly. This Postdoctober, we are spotlighting Jean Monlong, who has been a postdoc with the Genomics Institute since 2018. His research in Benedict Paten’s lab is part of a…