by tunhnguy | May 11, 2022 | News, Publications, Sequencing
Nurk, S., Koren, S., Rhie, A., Rautiainen, M., Bzikadze, A. V., Mikheenko, A., Vollger, M. R., Altemose, N., Uralsky, L., Gershman, A., Aganezov, S., Hoyt, S. J., Diekhans, M., Logsdon, G. A., Alonge, M., Antonarakis, S. E., Borchers, M., Bouffard, G. G., Brooks, S....
by tunhnguy | Feb 17, 2022 | Publications
Abstract Nanopore sequencing devices read individual RNA strands directly. This facilitatesidentification of exon linkages and nucleotide modifications; however, using conventional directRNA nanopore sequencing, the 5′ and 3′ ends of poly(A) RNA cannot be...
by ncharagu | Dec 22, 2021 | Publications
Sirén, Jouni, et al. “Pangenomics Enables Genotyping of Known Structural Variants in 5202 Diverse Genomes.” Science, vol. 374, no. 6574, 2021, https://doi.org/10.1126/science.abg8871.
by be-webmaster | Jun 9, 2021 | Publications, Sequencing
Abstract In 2001, Celera Genomics and the International Human Genome Sequencing Consortium published their initial drafts of the human genome, which revolutionized the field of genomics. While these drafts and the updates that followed effectively covered the...
by be-webmaster | Jun 2, 2021 | Publications
Abstract Cancer heterogeneity is a result of genetic mutations within the cancer cells. Their proliferation is not only driven by autocrine functions but also under the influence of cancer microenvironment, which consists of normal stromal cells such as infiltrating...
