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UCSC’s David Deamer and Mark Akeson honored for invention of nanopore sequencing

UCSC’s David Deamer and Mark Akeson honored for invention of nanopore sequencing

Today, two UC Santa Cruz researchers were honored at the Library of Congress for the invention of nanopore sequencing, which became a new and revolutionary method to read DNA and RNA. David Deamer and Mark Akeson, both emeritus professors of biomolecular engineering at the Baskin School of Engineering, received the American Association for the Advancement of Science’s (AAAS) Golden Goose Award for the invention.

Human Pangenome Named a GA4GH Driver Project

Human Pangenome Named a GA4GH Driver Project

GA4GH Driver Projects are real-world initiatives that help build and implement GA4GH standards, tools, and frameworks. They give voice to the broader genomics community and ensure GA4GH products serve real needs.

Innovation Catalyst Grants Fund Braingeneers Research

Innovation Catalyst Grants Fund Braingeneers Research

Haussler and Teodorescu were awarded $50,000 for their work in developing a revolutionary approach to cell culture that allows for more efficient testing on human organoids. Their innovation promises to significantly enhance the realism and scalability of experiments in biological research and will allow for new discoveries in cancer treatment, stroke, heart attack, and brain development research.

Yatish Turakhia one of “35 innovators under 35”

Yatish Turakhia one of “35 innovators under 35”

Former Genomics Institute postdoc Yatish Turakhia has been chosen as one of MIT Technology Review’s 2023 Innovators Under 35, in part for software tools he created at UC Santa Cruz to help track the Covid-19 pandemic. He is now evolving those tools so they can be used with other diseases.

New protocols make long-read sequencing feasible on larger scale

New protocols make long-read sequencing feasible on larger scale

Researchers at UC Santa Cruz’s Computational Genomics Lab and their collaborators have released new wet-lab and computational protocols that will make long-read sequencing feasible for large genomics projects. These protocols, which they have already implemented in a National Institute of Health project for Alzheimer’s research, will allow researchers to characterize regions of the genome that were previously inaccessible with short-read technology.

Novel device combines nanopores with electronic signals for disease detection

Novel device combines nanopores with electronic signals for disease detection

In living organisms, cells have a very high capacity to process and communicate information by moving molecules or ions through tiny channels that span the cell membrane. UC Santa Cruz Professor of Electrical and Computer Engineering Marco Rolandi’s lab and collaborators at MIT have created a device that mimics this biological concept in order to detect disease.

GREAT program creates new opportunities for students to participate in research

GREAT program creates new opportunities for students to participate in research

In the UC Santa Cruz Paleogenomics Lab, NSF postdoctoral fellow Andrew Sharo is using DNA from 100-year-old samples of steelhead trout to study how their populations have changed over time. It is important work — in California, local steelhead populations are endangered or threatened, and the answers Sharo finds in their genomes could help us figure out how this species has been impacted by habitat loss, introduced species, and climate change.

New blood test for noncoding RNA significantly improves cancer detection

New blood test for noncoding RNA significantly improves cancer detection

Cancer is most treatable in its early stages, so finding innovative and non-invasive methods to diagnose cancer early on is crucial for fighting the disease. Liquid biopsies, which require just a simple blood draw, are an emerging technology for non-invasively testing for cancer using DNA or RNA sequencing of a patient’s blood.

Ten Mysteries of the Y Chromosome

Ten Mysteries of the Y Chromosome

The Y chromosome is full of mysteries. What will researchers discover now that they have finally completed sequencing it? We share our top ten questions about the Y chromosome, and the answers we have so far!

Scientists release the first complete sequence of a human Y chromosome

Scientists release the first complete sequence of a human Y chromosome

For decades, the Y chromosome – one of the two human sex chromosomes – has been notoriously challenging for the genomics community to sequence due to the complexity of its structure. Now, this elusive area of the genome has been fully sequenced, a feat that finally completes the set of end-to-end human chromosomes and adds 30 million new bases to the human genome reference, mostly from challenging-to-sequence satellite DNA.