Publications

Featured Publications

Effects of Prolonged Media Usage and Long-term Planning on Archival Systems

Abstract: In archival systems, storage media are often replaced much earlier than their expected service life in exchange for other benefits of new media, such as higher capacity, bandwidth, and input/output operations per second, or lower costs. In an era of decreasing media density growth rates, retiring media early by considering only short-term benefits while…
Distinct patterns of somatic genome alterations in lung adenocarcinomas and squamous cell carcinomas

Abstract: To compare lung adenocarcinoma (ADC) and lung squamous cell carcinoma (SqCC) and to identify new drivers of lung carcinogenesis, we examined the exome sequences and copy number profiles of 660 lung ADC and 484 lung SqCC tumor-normal pairs. Recurrent alterations in lung SqCCs were more similar to those of other squamous carcinomas than to…
Genomic analysis of 6,000-year-old cultivated grain illuminates the domestication history of barley

Abstract: The cereal grass barley was domesticated about 10,000 years before the present in the Fertile Crescent and became a founder crop of Neolithic agriculture1. Here we report the genome sequences of five 6,000-year-old barley grains excavated at a cave in the Judean Desert close to the Dead Sea. Comparison to whole-exome sequence data from…