Publications

Featured Publications

The complete sequence of a human genome

In 2001, Celera Genomics and the International Human Genome Sequencing Consortium published their initial drafts of the human genome, which revolutionized the field of genomics. While these drafts and the updates that followed effectively covered the euchromatic fraction of the genome,
Cancer microenvironment and genomics: evolution in process

Abstract Cancer heterogeneity is a result of genetic mutations within the cancer cells. Their proliferation is not only driven by autocrine functions but also under the influence of cancer microenvironment, which consists of normal stromal cells such as infiltrating immune cells, cancer-associated fibroblasts, endothelial cells, pericytes, vascular and lymphatic channels. The relationship between cancer cells…
Oldest DNA sequences reveal how mammoths evolved

Caption: This illustration represents a reconstruction of the steppe mammoths that preceded the woolly mammoth, based on genetic analysis of ancient mammoth DNA. (Illustration by Beth Zaiken/Centre for Palaeogenetics) Analysis of ancient DNA sequences recovered from mammoth teeth reveal North American mammoths were descended from two earlier mammoth lineages February 17, 2021 | Tim Stephens…