Publications

  • The complete sequence of a human genome

    The complete sequence of a human genome

    Nurk, S., Koren, S., Rhie, A., Rautiainen, M., Bzikadze, A. V., Mikheenko, A., Vollger, M. R., Altemose, N., Uralsky, L., Gershman, A., Aganezov, S., Hoyt, S. J., Diekhans, M., Logsdon, G. A., Alonge, M., Antonarakis, S. E., Borchers, M., Bouffard, G. G., Brooks, S. Y., … Phillippy, A. M. (2022). The complete sequence of a…

  • Identification of high confidence human poly(A) RNA isoform scaffolds using nanopore sequencing

    Identification of high confidence human poly(A) RNA isoform scaffolds using nanopore sequencing

    [et_pb_section fb_built=”1″ _builder_version=”4.10.5″ _module_preset=”default” global_colors_info=”{}” custom_padding=”0px|||||”][et_pb_row _builder_version=”4.10.5″ _module_preset=”default” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.10.5″ _module_preset=”default” global_colors_info=”{}”][et_pb_text _builder_version=”4.10.5″ _module_preset=”default” global_colors_info=”{}”] Abstract Nanopore sequencing devices read individual RNA strands directly. This facilitatesidentification of exon linkages and nucleotide modifications; however, using conventional directRNA nanopore sequencing, the 5′ and 3′ ends of poly(A) RNA cannot be identifiedunambiguously. This is due in part…

Last modified: May 07, 2024